NHP2 Protein (His tag)

N° du produit ABIN7318843

Protéine Recombinant NHP2 exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour NHP2 Protein (His tag) (ABIN7318843)

Antigène: NHP2 (NHP2 Ribonucleoprotein (NHP2))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette NHP2 protéine est marqué à la His tag.

Fonction: Recombinant Human NHP2/NOLA2 Protein (His Tag)

Séquence: Met 1-Leu153

Attributs du produit: Recombinant Human Nucleolar protein family A member 2 is produced by our E.coli expression system and the target gene encoding Met1-Leu153 is expressed with a 6His tag at the N-terminus.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris,100 mM NaCl,1 mM DTT, pH 8.0.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: NHP2 (NHP2 Ribonucleoprotein (NHP2))

Autre désignation: NHP2/NOLA2

Sujet:

Background: NHP2 belongs to the H/ACA snoRNPs gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been organized into 2 families: C/D and H/ACA. NHP2 forms a small ribonucleoprotein particle with GAR1 (NOLA1). NHP2 is involved in a variety of aspects of rRNA processing and modification. NHP2 localizes to the dense fibrillar component of the nucleolus and in nuclear Cajal bodies. NHP2 may also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.

Synonym: H/ACA ribonucleoprotein complex subunit 2, Nucleolar protein family A member 2, snoRNP protein NHP2, NHP2, NOLA2, NHP2P.

Poids moléculaire: 19.3 kDa

UniProt: Q9NX24

Pathways: Telomere Maintenance