P-Cadherin Protein (CDH3) (Fc Tag)

N° du produit ABIN7320475

Cette protéine Recombinant P-Cadherin est exprimée dans Human Cells.

Aperçu rapide pour P-Cadherin Protein (CDH3) (Fc Tag) (ABIN7320475)

Antigène: P-Cadherin (CDH3)

Type de proteíne: Recombinant

Origine: Souris

Source: Human Cells

Pureté: > 90 % as determined by SDS-PAGE

Détail du produit

Purification/Conjugué: Cette P-Cadherin protéine est marqué à la Fc Tag.

Fonction: Recombinant Mouse Cadherin-3/CDH3 Protein (Fc Tag)

Séquence: Glu100-Gly647

Attributs du produit: Recombinant Mouse Cadherin-3 is produced by our Mammalian expression system and the target gene encoding Glu100-Gly647 is expressed with a Fc tag at the C-terminus.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: P-Cadherin (CDH3)

Autre désignation: Cadherin-3/CDH3

Sujet:

Background: Cadherin-3 (CDH3) is a single-pass type I membrane protein that belongs to the cadherin superfamily. CDH3 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. CDH3 is expressed in some normal epithelial tissues and in some carcinoma cell lines. CDH3 preferentially interacts with themselves in a homophilic manner in connecting cells. CDH3 is involved in loss of heterozygosity events in breast and prostate cancer. Mutations in CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.

Synonym: Cadherin-3, Placental cadherin, P-cadherin, Cdh3

Poids moléculaire: 87.5 kDa

UniProt: P10287