PON3 Protein (His tag)

N° du produit ABIN7317316

Cette protéine Recombinant PON3 est produite dans Baculovirus infected Insect Cells.

Aperçu rapide pour PON3 Protein (His tag) (ABIN7317316)

Antigène: PON3 (Paraoxonase 3 (PON3))

Type de proteíne: Recombinant

Origine: Humain

Source: Baculovirus infected Insect Cells

Pureté: > 85 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette PON3 protéine est marqué à la His tag.

Fonction: Recombinant Human PON3/Paraoxonase 3 Protein (50 Ser/Asn, His Tag)

Séquence: Met 1-Leu 354

Attributs du produit: A DNA sequence encoding the human PON3 (Q15166-1) (Met 1-Leu 354) (50 Ser/Asn) was expressed, with a polyhistidine tag at the N-terminus.

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.0, 1 mM CaCL2, 10 % glycerol, 0.1 % DDM

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: PON3 (Paraoxonase 3 (PON3))

Autre désignation: PON3/Paraoxonase 3

Sujet:

Background: KIR2DL4, also known as CD158d, is a member of the killer cell Ig-like receptor (KIR) family. KIRs are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous. KIR2DL4 is expressed in all NK cells and some T cells. KIR2DL4 activates the cytotoxicity of NK cells, despite the presence of an immunoreceptor tyrosine-based inhibition motif (ITIM) in its cytoplasmic tail. The ITIM was not necessary for activation of lysis by KIR2DL4. The activation signal of KIR2DL4 was sensitive to inhibition by another ITIM-containing receptor. The activation-deficient mutant of KIR2DL4 inhibited the signal delivered by the activating receptor CD16.

Synonym: PON3

Poids moléculaire: 42 kDa

Pathways: Monocarboxylic Acid Catabolic Process