PPIA Protéine
Aperçu rapide pour PPIA Protéine (ABIN7319370)
Antigène
Voir toutes PPIA ProtéinesType de proteíne
Origine
Source
Pureté
-
-
Fonction
- Recombinant Human Cyclophilin A Protein
-
Séquence
- Met 1-Glu165
-
Attributs du produit
- Recombinant Human Peptidyl-prolyl Cis-trans Isomerase A is produced by our E.coli expression system and the target gene encoding Met1-Glu165 is expressed.
-
niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
-
-
Vous souhaitez d'autres options pour ce Protein ?
!Découvrez nos protéines personnalisées prédéfinies et nos services de protéines sur mesure !ProduitSystème d'expressionConjuguéOriginPrix à partir deSystème d'expression HEK-293 CellsConjugué His tagOrigin HumanPrix à partir de 12.620,45 €Système d'expression Cell-free protein synthesis (CFPS)Conjugué Strep TagOrigin HumanPrix à partir de 18.117,43 €Votre projet nécessite-t-il une personnalisation supplémentaire ? Contactez-nous et découvrez nos solutions protéiques sur mesure
-
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Frozen, Liquid
-
Buffer
- Supplied as a 0.2 μm filtered solution of PBS, 10 % glycerol, pH 7.4 .
-
Stock
- -20 °C
-
Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
-
- PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))
-
Autre désignation
- Cyclophilin A
-
Sujet
-
Background: Peptidyl-prolyl cis-trans isomerase A is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds. Cyclophilin A regulate many biological processes, including intracellular signaling, transcription, inflammation, and apoptosis. Cyclophilin is also incorporated into many viruses, including HIV1, where it has been speculated to be involved in functions such as viral assembly and infectivity. The immunosuppressive activity of cyclosporins has been correlated with their ability to form complexes with cyclophilins that inhibit calcineurin phosphatase activity and prevent incorporation of cyclophilin into viral particles. The cyclosporin/cyclophilin complex selectively binds and inactivates calcineurin, making it a useful inhibitor for studying calcineurin activity.
Synonym: Peptidyl-prolyl cis-trans isomerase A, PPIase A, Cyclophilin A, Cyclosporin A-binding protein, Rotamase A, SP18, PPIA, CYPA
-
Poids moléculaire
- 18 kDa
-
UniProt
- P62937
Antigène
-