PMM2 Protein (His tag)

N° du produit ABIN7318900

Protéine Recombinant PMM2 exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour PMM2 Protein (His tag) (ABIN7318900)

Antigène: PMM2 (Phosphomannomutase 2 (PMM2))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette PMM2 protéine est marqué à la His tag.

Fonction: Recombinant Human PMM2 Protein (His Tag)

Séquence: Met 1-Ser246

Attributs du produit: Recombinant Human Phosphomannomutase 2 is produced by our E.coli expression system and the target gene encoding Met1-Ser246 is expressed with a 6His tag at the C-terminus.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: PMM2 (Phosphomannomutase 2 (PMM2))

Autre désignation: PMM2

Sujet:

Background: Phosphomannomutase 2 (PMM2) is an enzyme that is a member of the highly variable methyltransferase superfamily. PMM2 is a cytoplasmic protein and catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate.In addition, PMM2 involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose that required for a number of critical mannosyl transfer reactions. Defects in PMM2 can results in congenital disorder of glycosylation type 1A (CDG1A). Congenital disorders of glycosylation are metabolic deficiencies in glycoprotein biosynthesis that usually cause severe mental and psychomotor retardation.

Synonym: Phosphomannomutase 2, PMM 2, PMM2

Poids moléculaire: 29.1 kDa

UniProt: O15305