PDGF-AA Homodimer protein (His tag)

N° du produit ABIN7318911

Cette protéine Recombinant PDGF-AA Homodimer est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour PDGF-AA Homodimer protein (His tag) (ABIN7318911)

Antigène: PDGF-AA Homodimer

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: His tag

Fonction: Recombinant Human PDGF-AA Protein (His Tag)

Séquence: Ser87-Thr 211

Attributs du produit: Recombinant Human Platelet-derived growth factor AA is produced by our E.coli expression system and the target gene encoding Ser87-Thr211 is expressed with a 6His tag at the N-terminus.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: PDGF-AA Homodimer

Autre désignation: PDGF-AA

Sujet: PDGF subunit A,PDGF-1,PDGF1,PDGFA,Platelet-derived growth factor A chain,Platelet-derived growth factor alpha polypeptide,Platelet-derived growth factor subunit A,Platelet-derived growth factor subunit A (PDGFA), belongs to the PDGF/VEGF growth factor family. PDGFA is a secreted protein, stored in platelet alpha-granules and released by platelets upon wounding. PDGFA is potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. It plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. PDGFA is required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis, normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. It plays an important role in wound healing, Signaling is modulated by the formation of heterodimers with PDGFB.

Poids moléculaire:

Calculated MW: 15.9 kDa

Observed MW: 16 kDa

ID gène: 5154

UniProt: P04085