Prokineticin 1 Protein (Prok1) (His tag)
Aperçu rapide pour Prokineticin 1 Protein (Prok1) (His tag) (ABIN7318098)
Antigène
Voir toutes Prokineticin 1 (Prok1) ProtéinesType de proteíne
Origine
Source
Pureté
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Purification/Conjugué
- Cette Prokineticin 1 protéine est marqué à la His tag.
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Fonction
- Recombinant Human EG-VEGF/prokineticin-1 Protein (His Tag)
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Séquence
- Met 1-Phe105
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Attributs du produit
- A DNA sequence encoding the human EG-VEGF (Met 1-Phe105) (P58294) was expressed, with a C-terminal polyhistidine tag.
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 0.02 % Tween 80, 10 % glycerol, 1 mM DTT.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Agent conservateur
- Dithiothreitol (DTT)
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Précaution d'utilisation
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Date de péremption
- 12 months
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- Prokineticin 1 (Prok1)
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Autre désignation
- EG-VEGF/prokineticin-1
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Sujet
- EGVEGF,PK1,PRK1,EG-VEGF, also known as prokineticin-1, is a member of the AVIT (prokineticin) family. Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. EG-VEGF can be detected in the steroidogenic glands, ovary, testis, adrenal and placenta. EG-VEGF has little or no effect on a variety of other endothelial and non-endothelial cell types. It induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. EG-VEGF may play a role in placentation. It may also function in normal and pathological testis angiogenesis. It positively regulates PTGS2 expression and prostaglandin synthesis.
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Poids moléculaire
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Calculated MW: 11 kDa
Observed MW: 15 kDa
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ID gène
- 84432
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UniProt
- P58294
Antigène
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