PREP Protein (His tag)

N° du produit ABIN7197520

Détail du produit

Antigène: PREP (Prolyl Endopeptidase (PREP))

Type de proteíne: Recombinant

Origine: Souris

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette PREP protéine est marqué à la His tag.

Fonction: Recombinant Mouse Prolyl endopeptidase/PREP Protein (His Tag)

Séquence: Leu2-Gln710

Attributs du produit: A DNA sequence encoding the mature form of mouse PREP (Q9QUR6) (Leu2-Gln710) was expressed, with a polyhistidine tag at the N-terminus.

Pureté: > 95 % as determined by SDS-PAGE

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10 % glycerol, 3 mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: PREP (Prolyl Endopeptidase (PREP))

Autre désignation: Prolyl endopeptidase/PREP (PREP Produits)

Synonymes: PE Protein, PEP Protein, AI047692 Protein, AI450383 Protein, D10Wsu136e Protein, Pop Protein, rPop Protein, im:7140031 Protein, zgc:110670 Protein, prolyl endopeptidase Protein, Prolyl endopeptidase Protein, RB12337 Protein, AM1_4884 Protein, ppce Protein, PREP Protein, Prep Protein, prep Protein

Sujet:

Background: Prolyl endopeptidase, also known as PREP, belongs to a distinct class of serine peptidases. It is a large cytosolic enzyme which was first described in the cytosol of rabbit brain as an oligopeptidase. Prolyl endopeptidase degrades the nonapeptide bradykinin at the Pro-Phe bond. It is involved in the maturation and degradation of peptide hormones and neuropeptides such as alpha-melanocyte-stimulating hormone, luteinizing hormone-releasing hormone (LH-RH), thyrotropin-releasing hormone, angiotensin, neurotensin, oxytocin, substance P and vasopressin. Prolyl endopeptidase's activity is confined to action on oligopeptides of less than 10 kD and it has an absolute requirement for the trans-configuration of the peptide bond preceding proline. It cleaves peptide bonds at the C-terminal side of proline residues.

Synonym: AI047692,AI450383,D10Wsu136e,PEP,Pop

Poids moléculaire: 82.9 kDa

UniProt: Q9QUR6