PRCP Protein (His tag)
Aperçu rapide pour PRCP Protein (His tag) (ABIN7318751)
Antigène
Voir toutes PRCP ProtéinesType de proteíne
Origine
Source
Pureté
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Purification/Conjugué
- Cette PRCP protéine est marqué à la His tag.
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Fonction
- Recombinant Human PRCP Protein (His Tag)
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Séquence
- Leu22-His496
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Attributs du produit
- Recombinant Human Lysosomal Pro-X Carboxypeptidase is produced by our Mammalian expression system and the target gene encoding Leu22-His496 is expressed with a 6His tag at the C-terminus.
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niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM NaAc-HAc,150 mM NaCl,10 % Glycerol, pH 4.5.
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Stock
- -20 °C
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Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- PRCP (Prolylcarboxypeptidase (PRCP))
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Autre désignation
- PRCP
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Sujet
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Background: Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP is detected in many tissues, with highest levels observed in placenta, lung, and liver. It is also present in the heart, brain, pancreas, and kidney. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH , but enzymatic activity is retained with some substrates at neutral pH . PRCP has been shown to be an activator of the cell matrix-associated prekallikrein.
Synonym: Lysosomal Pro-X Carboxypeptidase, Angiotensinase C, Lysosomal Carboxypeptidase C, Proline Carboxypeptidase, Prolylcarboxypeptidase, PRCP, PRCP, PCP
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Poids moléculaire
- 54.5 kDa
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UniProt
- P42785
Antigène
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