PROS1 Protein (His tag)

N° du produit ABIN7197584

Protéine Recombinant PROS1 exprimée dans HEK-293 Cells.

Aperçu rapide pour PROS1 Protein (His tag) (ABIN7197584)

Antigène: PROS1 (PROS) (Protein S (PROS))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette PROS1 protéine est marqué à la His tag.

Fonction: Recombinant Human PROS1/Protein S Protein (His Tag)

Séquence: Met 1-Ser676

Attributs du produit: A DNA sequence encoding the human PROS1 (P07225) (Met1-Ser676) was expressed with a polyhistidine tag at the C-terminus.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: PROS1 (PROS) (Protein S (PROS))

Autre désignation: PROS1

Sujet: PROS,PS21,PS22,PS23,PS24,PS25,PSA,Protein S,THPH5,THPH6,PROS1, also known as protein S, is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. PROS1 has two isoforms: a free, functionally active form and an inactive form complexed with C4b-binding protein. Besides its anticoagulant function, PROS1 also acts as an agonist for the tyrosine kinase receptors Tyro3, Axl, and Mer. The endothelium expresses Tyro3, Axl, and Mer and produces protein S. The interaction of protein S with endothelial cells and particularly its effects on angiogenesis have not yet been analyzed.

Poids moléculaire:

Calculated MW: 74.1 kDa

Observed MW: 69-89 kDa

ID gène: 5627

UniProt: P07225