Resistin Protein (RETN) (His tag)

N° du produit ABIN7319264

Détail du produit

Antigène: Resistin (RETN)

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Resistin protéine est marqué à la His tag.

Fonction: Recombinant Human Resistin Protein (His Tag)

Séquence: Lys19-Pro108

Attributs du produit: Recombinant Human Adipose tissue-specific secretory factor is produced by our E.coli expression system and the target gene encoding Lys19-Pro108 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Acetic acid, pH 3.0.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Resistin (RETN)

Autre désignation: Resistin (RETN Produits)

Synonymes: RETN Protein, ADSF Protein, FIZZ3 Protein, RETN1 Protein, RSTN Protein, XCP1 Protein, Fizz3 Protein, Rstn Protein, Xcp4 Protein, resistin Protein, RETN Protein, Retn Protein

Sujet:

Background: Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. The length of the resistin pre-peptide in human is 108 amino acid residues and in the mouse and rat it is 114 aa, the molecular weight is ~12.5 kDa. Resistin is a cytokine whose physiologic role has been the subject of much controversy regarding its involvement with obesity and type II diabetes mellitus (T2DM). Resistin has been shown to cause "high levels of 'bad' cholesterol (low-density lipoprotein or LDL), increasing the risk of heart disease, resistin increases the production of LDL in human liver cells and also degrades LDL receptors in the liver. Potentially links obesity to diabetes.

Synonym: Resistin, Adipose tissue-specific secretory factor, Cysteine-rich secreted protein FIZZ3, C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-alpha-like 2, FIZZ3, HXCP1, RSTN, RETN,ADSF,FIZZ3,RETN1,XCP1

Poids moléculaire: 10.6 kDa

NCBI Accession: NP_065148

Pathways: Feeding Behaviour, Smooth Muscle Cell Migration