RNASET2 Protein (His tag)

N° du produit ABIN7197719

Protéine Recombinant RNASET2 exprimée dans Baculovirus infected Insect Cells.

Aperçu rapide pour RNASET2 Protein (His tag) (ABIN7197719)

Antigène: RNASET2 (Ribonuclease T2 (RNASET2))

Type de proteíne: Recombinant

Origine: Humain

Source: Baculovirus infected Insect Cells

Pureté: > 98 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette RNASET2 protéine est marqué à la His tag.

Fonction: Recombinant Human RNASET2 Protein (Baculovirus, His Tag)

Séquence: Met 1-His 256

Attributs du produit: A DNA sequence encoding the human RNASET2 isoform 1 (O00584-1) (Met 1-His 256) was fused with a polyhistidine tag at the C-terminus.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10 % glycerol
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: RNASET2 (Ribonuclease T2 (RNASET2))

Autre désignation: RNASET2

Sujet: 3.1.27.-,RNASE6PL,Ribonuclease 6,Ribonuclease T2,RNASET2 (ribonuclease T2) is an enzyme which belongs to the RNase T2 family. It is highly expressed in the temporal lobe and fetal brain. RNASET2 gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement. Defects in RNASET2 are the cause of leukoencephalopathy cystic without megalencephaly. An infantile-onset syndrome of cerebral leukoencephalopathy. Affected newborns develop microcephaly and neurologic abnormalities including psychomotor impairment, seizures and sensorineural hearing impairment. The brain shows multifocal white matter lesions, anterior temporal lobe subcortical cysts, pericystic abnormal myelination, ventriculomegaly and intracranial calcifications.

Poids moléculaire:

Calculated MW: 28.5 kDa

Observed MW: 35 kDa

ID gène: 8635

UniProt: O00584