SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N) (AA 1-419) (His tag)
Aperçu rapide pour SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N) (AA 1-419) (His tag) (ABIN7197805)
Antigène
Voir toutes SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) ProtéinesType de proteíne
Activité biologique
Origine
Source
Application
Pureté
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Attributs du protein
- AA 1-419
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Purification/Conjugué
- Cette SARS-CoV-2 Nucleocapsid protéine est marqué à la His tag.
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Fonction
- Recombinant SARS-CoV-2 Nucleocapsid Protein
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Séquence
- Met1-Ala419
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Attributs du produit
- Recombinant 2019-nCoV Nucleocapsid Protein is produced by our Mammalian expression system and the target gene encoding Met1-Ala419 is expressed with a 6His tag at the C-terminus.
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Stérilité
- 0.2 μm filtered
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Biological Activity Comment
- Immobilized 2019-nCoV NP Antibody(6G9)-Fc at 5μg/ml(100 μl/well) can bind Recombinant 2019-nCoV Nucleocapsid Protein (Mammalian)-His. The ED50 of 2019-nCoV Nucleocapsid Protein-His is 0.172 ug/ml.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 50 mM Tris-HCl, 150 mM NaCl, 50 mM Arginine, pH 7.5
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Stock
- -20 °C
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Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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Date de péremption
- 6 months
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- SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)
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Autre désignation
- SARS-CoV-2 Nucleocapsid
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Classe de substances
- Viral Protein
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Sujet
- SARS-CoV-2 coronavirus NP Protein,SARS-CoV-2 novel coronavirus Nucleoprotein Protein,SARS-CoV-2 np Protein,Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
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Poids moléculaire
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Calculated MW: 46.4 kDa
Observed MW: 50 kDa
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ID gène
- 43740568
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UniProt
- P0DTC2
Antigène
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