SRGN Protein (His tag)
Aperçu rapide pour SRGN Protein (His tag) (ABIN7317218)
Antigène
Voir toutes SRGN ProtéinesType de proteíne
Origine
Source
Pureté
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Purification/Conjugué
- Cette SRGN protéine est marqué à la His tag.
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Fonction
- Recombinant Human Serglycin/SRGN Protein (His Tag)
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Séquence
- Met 1-Leu158
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Attributs du produit
- A DNA sequence encoding the human SRGN (CAA34900.1) (Met1-Leu158) was expressed with a polyhistidine tag at the C-terminus.
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niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile PBS, pH 7.4
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- SRGN (serglycin (SRGN))
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Autre désignation
- Serglycin/SRGN
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Sujet
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Background: SRGN is known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of various hematopoietic cells has a protease-resistant peptide core, and is vital for neutralizing hydrolytic enzymes. SRGN is associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. It is required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. SRGN also plays a role in localizing neutrophil elastase in azurophil granules of neutrophils.
Synonym: PPG,PRG,PRG1
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Poids moléculaire
- 16.1 kDa
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Pathways
- Maintenance of Protein Location
Antigène
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