SRGN Protein (His-Myc tag)
Aperçu rapide pour SRGN Protein (His-Myc tag) (ABIN7317217)
Antigène
Voir toutes SRGN ProtéinesType de proteíne
Origine
Source
Pureté
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Purification/Conjugué
- Cette SRGN protéine est marqué à la His-Myc tag.
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Fonction
- Recombinant Human Serglycin/SRGN Protein (His&Myc Tag)
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Séquence
- Met 1-Leu158
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Attributs du produit
- A DNA sequence encoding the human SRGN (Met1-Leu158) was fused with the C-terminal polyhistidine-tagged myc at the C-terminus.
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Date de péremption
- 12 months
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- SRGN (serglycin (SRGN))
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Autre désignation
- Serglycin/SRGN
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Sujet
- PPG,PRG,PRG1,SRGN is known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of various hematopoietic cells has a protease-resistant peptide core, and is vital for neutralizing hydrolytic enzymes. SRGN is associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. It is required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. SRGN also plays a role in localizing neutrophil elastase in azurophil granules of neutrophils.
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Poids moléculaire
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Calculated MW: 17.3 kDa
Observed MW: 27 kDa
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ID gène
- 5552
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UniProt
- P10124
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Pathways
- Maintenance of Protein Location
Antigène
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