SIGLEC5 Protéine

N° du produit ABIN7317484

Cette protéine Recombinant SIGLEC5 est produite dans HEK-293 Cells.

Aperçu rapide pour SIGLEC5 Protéine (ABIN7317484)

Antigène: SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Pureté: > 85 % as determined by reducing SDS-PAGE.

Détail du produit

Fonction: Recombinant Human SIGLEC5 Protein

Séquence: Met 1-Thr 434

Attributs du produit: A DNA sequence encoding the human SIGLEC5 (O15389) (Met1-Thr 434) was expressed with six amino acids (LEVLFQ) at the C-terminus was expressed and purified.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))

Autre désignation: SIGLEC5

Sujet: CD170,CD33 antigen-like 2,CD33L2,OB-BP2,OBBP,OBBP2,Obesity-binding protein 2,SIGLEC-5,SIGLEC5,Sialic acid-binding Ig-like lectin 5,Siglec-5,SIGLEC5 contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. It belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC5 is expressed by monocytic/myeloid lineage cells. It is found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. It is also expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation. SIGLEC5 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

Poids moléculaire:

Calculated MW: 47.2 kDa

Observed MW: 67 kDa

ID gène: 8778

UniProt: O15389