TAO Kinase 3 Protein (TAOK3) (AA 1-411) (His-GST)

N° du produit ABIN7317073

Protéine Recombinant TAO Kinase 3 exprimée dans Baculovirus infected Insect Cells.

Aperçu rapide pour TAO Kinase 3 Protein (TAOK3) (AA 1-411) (His-GST) (ABIN7317073)

Antigène: TAO Kinase 3 (TAOK3)

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Baculovirus infected Insect Cells

Pureté: > 92 % as determined by reducing SDS-PAGE.

Détail du produit

Attributs du protein: AA 1-411

Purification/Conjugué: Cette TAO Kinase 3 protéine est marqué à la His-GST.

Fonction: Recombinant Human TAOK3/JIK/MAP3K18 Protein (aa 1-411, His & GST Tag)

Séquence: Met 1-Asp 411

Attributs du produit: A DNA sequence encoding the amino acids (Met 1-Asp 411) of human TAOK3 (Q9H2K8-1) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: The specific activity was determined to be 10 nmol/min/mg using synthetic PKCtide peptide (ERMRPRKRQGSVRRRV) as substrate.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, 3 mM GSH, pH 7.4, 10 % glycerol

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: TAO Kinase 3 (TAOK3)

Autre désignation: TAOK3/JIK/MAP3K18

Sujet: DPK,JIK,MAP3K18,Serine/threonine-protein kinase TAO3, also known as cutaneous T-cell lymphoma-associated antigen HD-CL-09, CTCL-associated antigen HD-CL-09, Dendritic cell-derived protein kinase, JNK / SAPK-inhibitory kinase, Jun kinase-inhibitory kinase, Kinase from chicken homolog A, Thousand and one amino acid protein 3, JIK, TAOK3 and MAP3K18, is cytoplasm and peripheral membrane protein which belongs to theprotein kinase superfamily, STE Ser/Thr protein kinase family and STE20 subfamily. Protein kinases are pivotal regulators of cell signaling that modulate each other's functions and activities through site-specific phosphorylation events. TAOK3 / JIK contains oneprotein kinase domain. TAOK3 / JIK is ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver. TAOK3 / JIK inhibits the basal activity of Jun kinase. It is negatively regulated by epidermal growth factor (EGF). When overexpressed, TAOK3 / JIK may activate ERK1 / ERK2 and JNK / SAPK.

Poids moléculaire:

Calculated MW: 74.3 kDa

Observed MW: 85 kDa

ID gène: 51347

UniProt: Q9H2K8