alpha Taxilin Protein (His tag)

N° du produit ABIN7319208

Cette protéine Recombinant alpha Taxilin est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour alpha Taxilin Protein (His tag) (ABIN7319208)

Antigène: alpha Taxilin (TXLNA) (Taxilin alpha (TXLNA))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette alpha Taxilin protéine est marqué à la His tag.

Fonction: Recombinant Human TXLNA Protein (His Tag)

Séquence: Met 1-Lys162

Attributs du produit: Recombinant Human alpha-Taxilin is produced by our E.coli expression system and the target gene encoding Met1-Lys162 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: alpha Taxilin (TXLNA) (Taxilin alpha (TXLNA))

Autre désignation: TXLNA

Sujet:

Background: α-Taxilin belongs to the taxilin family. α-Taxilin exists in almost all tissues, with higher expression levels observed in the heart, kidney, liver, and pancreas. α-Taxilin binds to the C-terminal coiled coil region of syntaxin family members STX1A, STX3A, and STX4A, but not when these proteins are complexed with SNAP25, VAMP2 or STXBP1, suggesting that it interacts with syntaxins that do not form the SNARE complex. It is shown that α-Taxilin plays multiple roles in the generation and maintenance of neurons through modulation of the NAC-mediated translational machinary and/or the syntaxin-mediated vesicle traffic in the soma. In addition, α-Taxilin may be involved in intracellular vesicle traffic and potentially in calcium-dependent exocytosis in neuroendocrine cells.

Synonym: Alpha-Taxilin, TXLNA, TXLN

Poids moléculaire: 20.4 kDa

UniProt: P40222