TSPAN1 Protein (Fc Tag)

N° du produit ABIN7317314

Détail du produit

Antigène: TSPAN1 (Tetraspanin 1 (TSPAN1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette TSPAN1 protéine est marqué à la Fc Tag.

Fonction: Recombinant Human TSPAN1 Protein (aa 110-211, Fc Tag)

Séquence: Tyr110-Asn211

Attributs du produit: A DNA sequence encoding the human TSPAN1 (O60635)(Tyr110-Asn211) was expressed with the Fc region of rabbit IgG at the N-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: TSPAN1 (Tetraspanin 1 (TSPAN1))

Autre désignation: TSPAN1 (TSPAN1 Produits)

Synonymes: TSPAN1 Protein, 9030418M05Rik Protein, NET1 Protein, TM4C Protein, TM4SF Protein, tetraspanin 1 Protein, tetraspanin 1 L homeolog Protein, TSPAN1 Protein, tspan1.L Protein, Tspan1 Protein

Sujet:

Background: TSPAN1 belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins have four hydrophobic domains, intracellular N- and C-termini and two extracellular domains. Tetraspanins act as scaffolding proteins, anchoring multiple proteins to one area of the cell membrane. They also mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TSPAN1 interacts with human thiamine transporter-1 (hTHTR-1). HTHTR-1 contributes to intestinal thiamine uptake, and its function is regulated at both the transcriptional and posttranscriptional levels. TSPAN1 and hTHTR-1 colocalize in human intestinal epithelial HuTu-80 cells. Coexpression of TSPAN1 in these cells led to a significant decrease in the rate of degradation of hTHTR-1 compared with cells expressing the hTHTR-1 alone, in fact the half-life of the TSPAN1 protein was twice longer in the former cell type compared with the latter cell type.

Synonym: NET1,TM4C,TM4SF,TSPAN1

Poids moléculaire: 39.1 kDa

UniProt: O60635