TIMP1 Protein (AA 25-205)

N° du produit ABIN7320662

Cette protéine Recombinant TIMP1 est exprimée dans HEK-293 Cells.

Aperçu rapide pour TIMP1 Protein (AA 25-205) (ABIN7320662)

Antigène: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Attributs du protein: AA 25-205

Fonction: Recombinant Mouse TIMP1/TIMP Protein

Séquence: Cys25-Arg205

Attributs du produit: Recombinant Mouse Tissue Inhibitors of Metalloproteinases 1 is produced by our Mammalian expression system and the target gene encoding Cys25-Arg205 is expressed.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Autre désignation: TIMP1/TIMP

Sujet: CLGI,Collagenase Inhibitor,EPA,Erythroid-Potentiating Activity,Fibroblast collagenase Inhibitor,Metalloproteinase Inhibitor 1,TIMP,TIMP-1,TIMP1,Tissue Inhibitor of Metalloproteinases 1,Mouse Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) is a member of TIMP family. The homologous proteins of TIMPs regulate the activity of matrix metalloproteinases (MMPs), including inhibition of active MMPs, proMMP activation, cell growth promotion, matrix binding, inhibition of angiogenesis and the induction of apoptosis. Timp-1 complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. It also mediates erythropoiesis in vitro, but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. It is known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16, without MMP-14.

Poids moléculaire:

Calculated MW: 20.2 kDa

Observed MW: 26 kDa

ID gène: 21857

UniProt: P12032