TLK1 Protein (His-GST)

N° du produit ABIN7317054

Cette protéine Recombinant TLK1 est produite dans Baculovirus infected Insect Cells.

Aperçu rapide pour TLK1 Protein (His-GST) (ABIN7317054)

Antigène: TLK1 (Tousled-Like Kinase 1 (TLK1))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Baculovirus infected Insect Cells

Pureté: > 88 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette TLK1 protéine est marqué à la His-GST.

Fonction: Recombinant Human TLK1/PKU-beta Protein (His & GST Tag)

Séquence: Met 1-Tyr 766

Attributs du produit: A DNA sequence encoding the human TLK1 isoform 1 (Q9UKI8-1) (Met 1-Tyr 766) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: The specific activity was determined to be 1. 6 nmol/min/mg using Histone H3 protein as substrate.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, pH 7.4, 10 % glycerol

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: TLK1 (Tousled-Like Kinase 1 (TLK1))

Autre désignation: TLK1/PKU-beta

Sujet: KIAA0137,PKU-beta,The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Calculated MW: 114 kDa

Observed MW: 125 kDa

ID gène: 9874

UniProt: Q9UKI8