Aperçu rapide pour TLK2 Protéine (ABIN7317071)
Antigène
Voir toutes TLK2 ProtéinesType de proteíne
Origine
Source
Pureté
-
-
Fonction
- Recombinant Human TLK2/PKU-ALPHA Protein
-
Séquence
- Leu 397-Asn772
-
Attributs du produit
- A DNA sequence encoding the human TLK2 (Q86UE8-1) (Leu397-Asn772) was fused with two additional amino acids (Gly & Pro) at the N-terminus.
-
niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
-
-
Vous souhaitez d'autres options pour ce Protein ?
!Découvrez nos protéines personnalisées prédéfinies et nos services de protéines sur mesure !ProduitSystème d'expressionConjuguéOriginPrix à partir deSystème d'expression HEK-293 CellsConjugué His tagOrigin HumanPrix à partir de 13.711,36 €Système d'expression Cell-free protein synthesis (CFPS)Conjugué Strep TagOrigin HumanPrix à partir de 20.480,57 €Votre projet nécessite-t-il une personnalisation supplémentaire ? Contactez-nous et découvrez nos solutions protéiques sur mesure
-
Tousled-Like Kinase 2 (TLK2) (AA 1-718) protein (His tag)
custom-made TLK2 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tousled-Like Kinase 2 (TLK2) (AA 1-772) protein (His tag)custom-made TLK2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tousled-Like Kinase 2 (TLK2) protein (GST tag,His tag)TLK2 Origine: Humain Hôte: Baculovirus infected Insect Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Tousled-Like Kinase 2 (TLK2) (Transcript Variant A) protein (Myc-DYKDDDDK Tag)TLK2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Frozen, Liquid
-
Buffer
- Supplied as sterile 20 mM Tris, 500 mM NaCl, 3 mM DTT, 10 % glycerol, pH 8.0
-
Stock
- -20 °C
-
Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
-
- TLK2 (Tousled-Like Kinase 2 (TLK2))
-
Autre désignation
- TLK2/PKU-ALPHA
-
Sujet
-
Background: Serine / threonine-protein kinase tousled-like 2; also known as PKU-alpha; Tousled-like kinase 2 and TLK2; is a nucleus protein which belongs to the protein kinase superfamily and Ser/Thr protein kinase family. The tousled-like kinases are an evolutionarily conserved family of proteins implicated in DNA repair; DNA replication and mitosis in metazoans and plants. Their absence from the yeasts and other eukaryotic 'microbes' suggests a specific role for them in the development of multicellular organisms. Tousled-like kinase 2 / TLK2 is widely expressed. It is present in fetal placenta; liver; kidney; pancreas; heart and skeletal muscle. It is also found in adult cell lines. Tousled-like kinase 2 / TLK2 contains one protein kinase domain. Tousled-like kinase 2 / TLK2 is rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly.
Synonym: HsHPK;PKU-ALPHA
-
Poids moléculaire
- 43.6 kDa
Antigène
-
