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TGFB2 Protéine

Protéine Recombinant TGFB2 exprimée dans Human Cells.
N° du produit ABIN7320669

Aperçu rapide pour TGFB2 Protéine (ABIN7320669)

Antigène

Voir toutes TGFB2 Protéines
TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Type de proteíne

Recombinant

Activité biologique

Active

Origine

  • 15
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Souris

Source

  • 23
  • 5
  • 5
  • 5
  • 1
  • 1
  • 1
Human Cells

Pureté

> 95 % as determined by SDS-PAGE
  • Fonction

    Recombinant Mouse TGFB2 Protein (Active)

    Séquence

    Ala303-Ser414

    Attributs du produit

    Recombinant Mouse Transforming Growth Factor beta 2 is produced by our Mammalian expression system and the target gene encoding Ala303-Ser414 is expressed.

    niveau d'endotoxine

    < 1.0 EU per μg as determined by the LAL method.

    Biological Activity Comment

    Immobilized Mouse TGFB2 at 10μg/ml(100 μl/well) can bind Human TGFBR2-FC(Cat: PKSH033426). The ED50 of Mouse TGFB2 is 22μg/mL.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.

    Stock

    4 °C,-20 °C,-80 °C

    Stockage commentaire

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène

    TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

    Autre désignation

    TGFB2

    Sujet

    Background: Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.

    Synonym: TGFB2, BSC-1 cell growth inhibitor, Cetermin, Glioblastoma-derived T-cell suppressor factor, G-TSF, MGC116892, Polyergin, TGF-beta2, TGF-beta-2, transforming growth factor beta-2

    Poids moléculaire

    12.7 kDa

    UniProt

    P27090

    Pathways

    Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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