TGFB2 Protéine
Aperçu rapide pour TGFB2 Protéine (ABIN7320669)
Antigène
Voir toutes TGFB2 ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Fonction
- Recombinant Mouse TGFB2 Protein (Active)
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Séquence
- Ala303-Ser414
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Attributs du produit
- Recombinant Mouse Transforming Growth Factor beta 2 is produced by our Mammalian expression system and the target gene encoding Ala303-Ser414 is expressed.
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niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
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Biological Activity Comment
- Immobilized Mouse TGFB2 at 10μg/ml(100 μl/well) can bind Human TGFBR2-FC(Cat: PKSH033426). The ED50 of Mouse TGFB2 is 22μg/mL.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))
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Autre désignation
- TGFB2
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Sujet
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Background: Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.
Synonym: TGFB2, BSC-1 cell growth inhibitor, Cetermin, Glioblastoma-derived T-cell suppressor factor, G-TSF, MGC116892, Polyergin, TGF-beta2, TGF-beta-2, transforming growth factor beta-2
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Poids moléculaire
- 12.7 kDa
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UniProt
- P27090
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Pathways
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
Antigène
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