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TPBG Protein (mFc Tag)

TPBG Origine: Humain Hôte: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7319827
  • Antigène Voir toutes TPBG Protéines
    TPBG (Trophoblast Glycoprotein (TPBG))
    Type de proteíne
    Recombinant
    Origine
    • 16
    • 5
    • 3
    • 2
    • 1
    Humain
    Source
    • 15
    • 4
    • 2
    • 2
    • 2
    • 1
    Human Cells
    Purification/Conjugué
    Cette TPBG protéine est marqué à la mFc Tag.
    Fonction
    Recombinant Human TPBG/5T4 (C-mFc)
    Séquence
    Ser32-Ser355
    Attributs du produit
    Recombinant Human Trophoblast glycoprotein is produced by our Mammalian expression system and the target gene encoding Ser32-Ser355 is expressed with a mFc tag at the C-terminus.
    Pureté
    >95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product TPBG Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène
    TPBG (Trophoblast Glycoprotein (TPBG))
    Autre désignation
    TPBG/5T4 (TPBG Produits)
    Synonymes
    5T4 Protein, 5T4AG Protein, M6P1 Protein, AW495680 Protein, TPBG Protein, tpbg Protein, trophoblast glycoprotein Protein, trophoblast glycoprotein b Protein, TPBG Protein, Tpbg Protein, tpbgb Protein, tpbg Protein
    Sujet

    Background: Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap (LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.

    Synonym: 5T4 , 5T4AG, M6P1, WAIF1

    Poids moléculaire
    61.7 kDa
    UniProt
    Q13641
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