CD160 Protein (CD160) (Fc Tag)

N° du produit ABIN7321007

Protéine Recombinant CD160 exprimée dans Human Cells.

Aperçu rapide pour CD160 Protein (CD160) (Fc Tag) (ABIN7321007)

Antigène: CD160

Type de proteíne: Recombinant

Origine: Macaque rhésus

Source: Human Cells

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette CD160 protéine est marqué à la Fc Tag.

Fonction: Recombinant Rhesus macaque CD160 Protein (Fc Tag)

Séquence: Met1-Leu158

Attributs du produit: Recombinant Rhesus macaque CD160 is produced by our Mammalian expression system and the target gene encoding Met1-Leu158 is expressed with a Fc tag at the C-terminus.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Commentaires:

55-65 kDa

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: CD160

Autre désignation: CD160

Sujet:

Background: CD160 antigen is a cell membrane protein which contains one Ig-likeV-type (immunoglobulin-like) domain. CD160 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim) CD16(+)peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 is expressed in spleen,peripheral blood,and small intestine. Expression of CD160 is restricted to functional NK and T cytotoxic lymphocytes. CD160 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD160+ T cells isolated from inflammatory skin lesions. Activated NK lymphocytes release a soluble form of CD160 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymphocyte responsiveness.

Synonym: CD160 antigen, CD160

Poids moléculaire: 45 kDa

UniProt: G7MG20