IL-33 Protein (His tag)

N° du produit ABIN7320998

Cette protéine Recombinant IL-33 est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour IL-33 Protein (His tag) (ABIN7320998)

Antigène: IL-33 (IL33) (Interleukin 33 (IL33))

Type de proteíne: Recombinant

Origine: Macaque rhésus

Source: Escherichia coli (E. coli)

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette IL-33 protéine est marqué à la His tag.

Fonction: Recombinant Rhesus macaque IL-33/Interleukin-33 Protein (His Tag)

Séquence: Ser112-Ile270

Attributs du produit: Recombinant Rhesus macaque Interleukin 33 is produced by our E.coli expression system and the target gene encoding Ser112-Ile270 is expressed with a 6His tag at the N-terminus.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Commentaires:

21 kDa

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: IL-33 (IL33) (Interleukin 33 (IL33))

Autre désignation: IL-33/Interleukin-33

Sujet:

Background: Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.

Synonym: Interleukin-33, IL-33, Interleukin-1 Family Member 11, IL-1F11, Nuclear Factor From High Endothelial Venules, NF-HEV, IL33, C9orf26, IL1F11, NFHEV

Poids moléculaire: 20.3 kDa

UniProt: F7DLG4

Pathways: Production of Molecular Mediator of Immune Response