TNNC1 Protéine
Aperçu rapide pour TNNC1 Protéine (ABIN7317698)
Antigène
Voir toutes TNNC1 ProtéinesType de proteíne
Origine
Source
Pureté
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Fonction
- Recombinant Human Troponin C/TNNC1 Protein
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Séquence
- Met 1-Glu161
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Attributs du produit
- A DNA sequence encoding the human TNNC1 (NP_003271.1) (Met1-Glu161) was expressed and purified.
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Stérilité
- 0.2 μm filtered
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Biological Activity Comment
- Not validated for activity
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Cardiac Troponin C (TNNC1) (AA 1-161) protein (His tag)
custom-made TNNC1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cardiac Troponin C (TNNC1) (AA 1-161) protein (His tag)custom-made TNNC1 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cardiac Troponin C (TNNC1) (AA 1-161) protein (His-IF2DI Tag)TNNC1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Cardiac Troponin C (TNNC1) (AA 1-161) protein (GST tag)TNNC1 Origine: Humain Hôte: Wheat germ Recombinant AP, AA, ELISA, WB
Cardiac Troponin C (TNNC1) protein (Myc-DYKDDDDK Tag)TNNC1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile 150 mM NaCl, 10 mM Na2HPO4, pH 7.5
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Date de péremption
- 12 months
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- TNNC1 (Cardiac Troponin C (TNNC1))
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Autre désignation
- TNNC1
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Sujet
- CMD1Z,CMH13,TN-C,TNC,TNNC,Troponin I, also known as TNNC1, is part of the troponin complex. This complex contains 3 subunits: troponin I (TnI), troponin T (TnT) and troponin C (TnC). Troponin I is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.
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Poids moléculaire
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Calculated MW: 18.4 kDa
Observed MW: 20 kDa
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ID gène
- 7134
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NCBI Accession
- NP_003271
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UniProt
- P63316
Antigène
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