Follistatin Protein (FST)
Aperçu rapide pour Follistatin Protein (FST) (ABIN7319608)
Antigène
Voir toutes Follistatin (FST) ProtéinesType de proteíne
Origine
Source
Pureté
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Fonction
- Recombinant Human Follistatin 288/FST Protein
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Séquence
- Gly30-Asn317
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Attributs du produit
- Recombinant Human Follistatin is produced by our Mammalian expression system and the target gene encoding Gly30-Asn317 is expressed.
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niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
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Commentaires
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33-42 kDa
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Follistatin (FST)
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Autre désignation
- FST
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Sujet
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Background: Follistatin 288 is a secreted glycoprotein that was first identified as a follicle-stimulating hormone inhibiting substance in ovarian follicular fluid. Human follistatin 288 cDNA encodes a 317 amino acid (aa) protein with a 29aa signal sequence, and a 288 aa mature region.Follistatin shows the highest affinity for activins due to its extended configuration. Genetic deletion of follistatin in mice, or expression of only the Follistatin form, is perinatally lethal due to defects of lung, skin and musculoskeletal system. Follistatins also regulate hematopoietic stem cell adhesion to fibronectin via FS2.
Synonym: follistatin isoform FST317, Follistatin, FS, FSActivin-binding protein, FST
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Poids moléculaire
- 32.4 kDa
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UniProt
- P19883
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Pathways
- Negative Regulation of Hormone Secretion
Antigène
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