Tryptophan Synthetase protein (His tag)

N° du produit ABIN7320985

Cette protéine Recombinant Tryptophan Synthetase est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour Tryptophan Synthetase protein (His tag) (ABIN7320985)

Antigène: Tryptophan Synthetase

Type de proteíne: Recombinant

Origine: E. coli

Source: Escherichia coli (E. coli)

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: His tag

Fonction: Recombinant E.coli Tryptophan Synthase Protein (His Tag)

Séquence: Met1-Ser268&Thr2-Ile397

Attributs du produit: Recombinant E.coli Tryptophan synthase is produced by our E.coli expression system and the target gene encoding Met1-Ser268&Thr2-Ile397 is expressed with a 6His tag at the N-terminus.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Commentaires:

28&40-50 kDa

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: Tryptophan Synthetase

Autre désignation: Tryptophan Synthase

Sujet:

Background: Tryptophan synthase is a multienzyme α2β2 complex composed of two protein subunit. Tryptophan synthase catalyzes the last two steps in the synthesis of L-tryptophan (L-Trp). The α-subunit catalyzes cleavage of 3-indole-d-glycerol 3'-phosphate (IGP) to give indole and D-glyceraldehyde 3'-phosphate (G3P). Indole is then transferred through a 25-? hydrophobic tunnel to the β-subunit. The β2 subunit contains pyridoxal 5'-phosphate and catalyzes several pyridoxal 5'-phosphate-dependent reactions, including/3-elimination reactions 6 and a thiol-dependent transamination reaction. This enzyme is commonly found in Eubacteria, Archaebacteria, Protista, Fungi, and Plantae, but is absent from Animalia. As humans do not have tryptophan synthase, this enzyme has been explored as a potential drug target.

Synonym: Tryptophan synthetase, Tryptophan synthase

Poids moléculaire: 72.5 kDa