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CD52 Protein (CD52) (Biotin)

CD52 Origine: Humain Hôte: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7319777
  • Antigène Voir toutes CD52 Protéines
    CD52
    Type de proteíne
    Recombinant
    Origine
    • 10
    • 2
    Humain
    Source
    • 9
    • 1
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette CD52 protéine est marqué à la Biotin.
    Fonction
    Recombinant Human CD52 (C-Fc-Avi) Biotinylated
    Séquence
    Gly25-Ser36
    Attributs du produit
    Biotinylated Recombinant Human CAMPATH-1 Antigen is produced by our Mammalian expression system and the target gene encoding Gly25-Ser36 is expressed with a Fc, Avi tag at the C-terminus.
    Pureté
    >95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CD52 Protéine
  • Commentaires

    38-50 kDa

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène
    CD52
    Autre désignation
    CD52 (CD52 Produits)
    Synonymes
    CD52 Protein, AI463198 Protein, B7 Protein, B7-Ag Protein, CAMPATH-1 Protein, CLS1 Protein, MB7 Protein, CDW52 Protein, CE5 Protein, CD52 molecule Protein, CD52 antigen Protein, CD52 Protein, Cd52 Protein
    Sujet

    Background: CD52, also known as CAMPATH-1 antigen, HE5, and gp20, is a cell surface glycoprotein that can be targeted to induce immune suppression by complement-mediated cell lysis. CD52 is expressed on lymphocytes, monocytes, monocycte-derived dendritic cells, eosinophils, and neutrophils, as well as on mature spermatozoa and epithelial cells lining the male genital tract. From the clinical point of view this protein is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. CD52 / CDW52 may play a role in carrying and orienting carbohydrate. It is an unusually good target for complement-mediated cell lysis.

    Synonym: CAMPATH-1 antigen, CAMPATH-1, CD52 antigen, CD52 Molecule, CD52,  CDw52, Epididymal secretory protein E5, He5, HEL-S-171mP, Human epididymis-specific protein 5

    Poids moléculaire
    30.2 kDa
    UniProt
    P31358
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