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HLA-A*01:01 protein (SBP Tag)

Protéine Recombinant exprimée dans Mammalian Cells.
N° du produit ABIN7273160

Aperçu rapide pour HLA-A*01:01 protein (SBP Tag) (ABIN7273160)

Antigène

HLA-A*01:01

Type de proteíne

Recombinant

Origine

Humain

Source

  • 5
Mammalian Cells

Application

Blocking Peptide (BP), Control Peptide (CP), ELISA, Neutralization (Neut)

Pureté

> 80 %
  • Purification/Conjugué

    SBP Tag

    Fonction

    The product is HLA-A*01:01 complexed with β2-microglobulin (b2m)

    Séquence

    heavy chain: GSHSMRYFFT SVSRPGRGEP RFIAVGYVDD TQFVRFDSDA ASQKMEPRAP WIEQEGPEYW DQETRNMKAH SQTDRANLGT LRGYYNQSED GSHTIQIMYG CDVGPDGRFL RGYRQDAYDG KDYIALNEDL RSWTAADMAA QITKRKWEAV HAAEQRRVYL EGRCVDGLRR YLENGKETLQ RTDPPKTHMT HHPISDHEAT LRCWALGFYP AEITLTWQRD GEDQTQDTEL VETRPAGDGT FQKWAAVVVP SGEEQRYTCH VQHEGLPKPL TLRWELSSQP TIPI
    light chain: IQRTPKIQVY SRHPAENGKS NFLNCYVSGF HPSDIEVDLL KNGERIEKVE HSDLSFSKDW SFYLLYYTEF TPTEKDEYAC RVNHVTLSQP KIVKWDRDM
    Sequences without tags. Tag location is at the discretion of the manufacturer.

    Specificité

    HLA-A*01:01 complexed with b2m, P04439 / P61769

    Attributs du produit

    HLAs are produced in mammalian cell cultures as recombinant, truncated, soluble antigens, in complex with β2-microglobulin (HLA class I). As part of our quality control, all HLA are analyzed for purity by gel electrophoresis, concentration is determined by ELISA (0.5 mg/ml) and their functionality is verified with a specific antiserum.

    Purification

    Chromatography

    niveau d'endotoxine

    Endotoxins have not been removed
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  • Indications d'application

    ELISA: 1 - 100 ng/mL

    Commentaires

    sandwich ELISA, direct ELISA, bead ELISA, reactive with antibodies W6/32 and BBM.1 and specific antiserum, B cell ELI Spot (predicted), in vitro memory B cell stimulation (predicted), HLA competition assay (predicted), control in various assays (predicted)

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.5 mg/mL

    Buffer

    TRIS based buffer, pH 8.0, Sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C

    Date de péremption

    6 months
  • Antigène

    HLA-A*01:01

    Sujet

    Human Leukozyte Antigen, human Antigen-presenting major histocompatibility complex class I (MHCI) molecule. Expressed on all cells, displays peptides to CD8-positive T cells. Involved in cellular immune response.

    Poids moléculaire

    approx. 50 kDa (38 kDa heavy chain + 12 kDa b2m)

    UniProt

    P04439
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