HLA-B*18:01 protein (SBP Tag)

N° du produit ABIN7273192

Cette protéine Recombinant est exprimée dans Mammalian Cells.

Aperçu rapide pour HLA-B*18:01 protein (SBP Tag) (ABIN7273192)

Antigène: HLA-B*18:01

Type de proteíne: Recombinant

Origine: Humain

Source: Mammalian Cells

Application: Blocking Peptide (BP), Control Peptide (CP), ELISA, Neutralization (Neut)

Pureté: > 80 %

Détail du produit

Purification/Conjugué: SBP Tag

Fonction: The product is HLA-B*18:01 complexed with β2-microglobulin (b2m)

Séquence: heavy chain: GSHSMRYFYT AMSRPGRGEP RFISVGYVDD TQFVRFDSDA ASPREEPRAP WIEQEGPEYW DRNTQICKTN TQTYRESLRN LRGYYNQSEA GSHTLQRMYG CDVGPDGRLL RGHDQSAYDG KDYIALNEDL SSWTAADTAA QITQRKWEAA REAEQLRAYL EGLCVEWLRR YLENGKETLQ RADPPKTHVT HHPISDHEAT LRCWALGFYP AEITLTWQRD GEDQTQDTEL VETRPAGDRT FQKWAAVVVP SGEEQRYTCH VQHEGLPKPL TLRWEPSSQS TIPI
light chain: IQRTPKIQVY SRHPAENGKS NFLNCYVSGF HPSDIEVDLL KNGERIEKVE HSDLSFSKDW SFYLLYYTEF TPTEKDEYAC RVNHVTLSQP KIVKWDRDM
Sequences without tags. Tag location is at the discretion of the manufacturer.

Specificité: HLA-B*18:01 complexed with b2m, P01889 / P61769
HLA-B*B18:01 is most common in Nothern Italy and the Balkans with an average frequency of up to 17%. It reacts with anti-Bw6 antibodies.

Attributs du produit: HLAs are produced in mammalian cell cultures as recombinant, truncated, soluble antigens, in complex with β2-microglobulin (HLA class I). As part of our quality control, all HLA are analyzed for purity by gel electrophoresis, concentration is determined by ELISA (0.5 mg/ml) and their functionality is verified with a specific antiserum.

Purification: Chromatography

niveau d'endotoxine: Endotoxins have not been removed

Information d'application

Indications d'application: ELISA: 1 - 100 ng/mL

Commentaires:

sandwich ELISA, direct ELISA, bead ELISA, reactive with antibodies W6/32 and BBM.1 and specific antiserum, B cell ELI Spot (predicted), in vitro memory B cell stimulation (predicted), HLA competition assay (predicted), control in various assays (predicted)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: TRIS based buffer, pH 8.0, Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 6 months

Détail du antigène

Antigène: HLA-B*18:01

Sujet: Human Leukozyte Antigen, human Antigen-presenting major histocompatibility complex class I (MHCI) molecule. Expressed on all cells, displays peptides to CD8-positive T cells. Involved in cellular immune response.

Poids moléculaire: approx. 50 kDa (38 kDa heavy chain + 12 kDa b2m)

UniProt: P01889