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CD200 Protein (CD200) (AA 31-232) (His tag)

Cette protéine Recombinant CD200 est produite dans HEK-293 Cells.
N° du produit ABIN7274106

Aperçu rapide pour CD200 Protein (CD200) (AA 31-232) (His tag) (ABIN7274106)

Antigène

Voir toutes CD200 Protéines
CD200

Type de proteíne

Recombinant

Origine

  • 20
  • 12
  • 2
  • 1
Humain

Source

  • 13
  • 4
  • 4
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Pureté

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • Attributs du protein

    AA 31-232

    Purification/Conjugué

    Cette CD200 protéine est marqué à la His tag.

    Fonction

    Human CD200/OX-2 Protein

    Séquence

    Gln31-Gly232

    Attributs du produit

    Recombinant Human CD200/OX-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln31-Gly232.

    Stérilité

    0.22 μm filtered

    niveau d'endotoxine

    Less than 1EU per μg by the LAL method.

    Biological Activity Comment

    Immobilized Human CD200 at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Human CD200 R1, hFc Tag with the EC50 18ng/ml determined by ELISA. See testing image for detail.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    Buffer

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    -20 to -80°C for 24 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Date de péremption

    12 months
  • Antigène

    CD200

    Autre désignation

    CD200

    Sujet

    CD200 and its receptors are highly expressed in the lung, on epithelial cells and leukocytes, and emerging evidence links dysregulation of the CD200 pathway with asthma. Moreover, pharmacological modulation of CD200 receptors was shown to improve clinical and inflammatory outcomes of preclinical asthma models.

    Poids moléculaire

    23.5 kDa. Due to glycosylation, the protein migrates to 40-60 kDa based on Tris-Bis PAGE result.

    UniProt

    P41217-1
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