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CD93 Protein (CD93) (AA 22-580) (Fc Tag)

Cette protéine Recombinant CD93 est produite dans HEK-293 Cells.
N° du produit ABIN7274268

Aperçu rapide pour CD93 Protein (CD93) (AA 22-580) (Fc Tag) (ABIN7274268)

Antigène

Voir toutes CD93 Protéines
CD93

Type de proteíne

Recombinant

Origine

  • 15
  • 3
  • 2
  • 1
Humain

Source

  • 8
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
HEK-293 Cells

Pureté

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • Attributs du protein

    AA 22-580

    Purification/Conjugué

    Cette CD93 protéine est marqué à la Fc Tag.

    Fonction

    Human CD93/C1q R1 Protein

    Séquence

    Thr22-Lys580

    Attributs du produit

    Recombinant Human CD93/C1q R1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Thr22-Lys580.

    Stérilité

    0.22 μm filtered

    niveau d'endotoxine

    Less than 1EU per μg by the LAL method.

    Biological Activity Comment

    Immobilized Human IGFBP-7, His Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Human CD93, hFc Tag with the EC50 of 2.6μg/ml determined by ELISA. See testing image for detail.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    Buffer

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Date de péremption

    12 months
  • Antigène

    CD93

    Autre désignation

    CD93

    Sujet

    CD93 has been shown critical roles in inflammatory and immune diseases. CD93 silencing increased IL-6 and TSLP, but not IL-33 levels in culture supernatants. HDM-induced asthma mice showed significant airway hyperresponsiveness and inflammation with Th2 cytokine activation, along with decreased CD93 expression in bronchial epithelial cells and lung homogenates but increased serum CD93 levels.

    Poids moléculaire

    85 kDa. Due to glycosylation, the protein migrates to 115-120 kDa based on Tris-Bis PAGE result.

    UniProt

    Q9NPY3
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