SARS-CoV NSP3 Protein (AA 1564-1880) (His tag)

N° du produit ABIN7274382

Cette protéine Recombinant SARS-CoV NSP3 est produite dans Escherichia coli (E. coli).

Aperçu rapide pour SARS-CoV NSP3 Protein (AA 1564-1880) (His tag) (ABIN7274382)

Antigène: SARS-CoV NSP3 (SARS-Coronavirus Nonstructural Protein 3 (SARS-CoV NSP3))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: SARS Coronavirus-2 (SARS-CoV-2)

Source: Escherichia coli (E. coli)

Pureté: > 95 % as determined by Bis-Tris PAGE

Détail du produit

Attributs du protein: AA 1564-1880

Purification/Conjugué: Cette SARS-CoV NSP3 protéine est marqué à la His tag.

Fonction: SARS-COV-2 PLpro/papain-like protease Protein

Séquence: Glu1564-Val1880

Attributs du produit: Recombinant SARS-COV-2 PLpro/papain-like protease Protein is expressed from E.coli with His tag at the N-Terminus.It contains Glu1564-Val1880.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: SARS-COV-2 PLpro on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in 20 mM Tris, 100 mM NaCl, 10 % Glycerol ( pH 8.5).

Stock: -80 °C

Stockage commentaire: Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: SARS-CoV NSP3 (SARS-Coronavirus Nonstructural Protein 3 (SARS-CoV NSP3))

Autre désignation: PLpro

Classe de substances: Viral Protein

Sujet: The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses.

Poids moléculaire: 39.2 kDa same as Bis-Tris PAGE result.

NCBI Accession: YP_009725299