MFAP4 Protein (AA 60-293) (His tag)

N° du produit ABIN7275229

Cette protéine Recombinant MFAP4 est exprimée dans HEK-293 Cells.

Aperçu rapide pour MFAP4 Protein (AA 60-293) (His tag) (ABIN7275229)

Antigène: MFAP4 (Microfibrillar-Associated Protein 4 (MFAP4))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Cynomolgus

Source: HEK-293 Cells

Pureté: > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC

Détail du produit

Attributs du protein: AA 60-293

Purification/Conjugué: Cette MFAP4 protéine est marqué à la His tag.

Fonction: Cynomolgus MFAP4 Protein

Séquence: Val60-Ala293

Attributs du produit: Recombinant Cynomolgus MFAP4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val60-Ala293.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: Immobilized Cynomolgus MFAP4, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-MFAP4 Antibody, hFc Tag with the EC50 of 3.2ng/ml determined by ELISA.,Cynomolgus MFAP4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Cynomolgus MFAP4 is greater than 95% as determined by SEC-HPLC.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 24 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 24 months

Détail du antigène

Antigène: MFAP4 (Microfibrillar-Associated Protein 4 (MFAP4))

Autre désignation: MFAP4

Sujet: Microfibril-associated glycoprotein 4 (MFAP4) is an extracellular matrix protein belonging to the fibrinogen-related protein superfamily. MFAP4 is produced by vascular smooth muscle cells and is highly enriched in the blood vessels of the heart and lung, where it is thought to contribute to the structure and function of elastic fibers. Genetic studies in humans have implicated MFAP4 in the pathogenesis of Smith-Magenis syndrome, in which patients present with multiple congenital abnormalities and mental retardation, as well as in the severe cardiac malformation left-sided congenital heart disease.

Poids moléculaire: 27.60 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Bis-Tris PAGE result.

UniProt: A0A2K5TQS8