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NKG2C & CD94 (AA 98-231) protein (His-Avi Tag)

Cette protéine Recombinant est produite dans HEK-293 Cells.
N° du produit ABIN7275330

Aperçu rapide pour NKG2C & CD94 (AA 98-231) protein (His-Avi Tag) (ABIN7275330)

Antigène

NKG2C & CD94

Type de proteíne

Recombinant

Origine

  • 3
  • 1
Humain

Source

  • 4
HEK-293 Cells

Pureté

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • Attributs du protein

    AA 98-231

    Purification/Conjugué

    His-Avi Tag

    Fonction

    Human NKG2C&CD94 Protein

    Séquence

    Glu98-Leu231(NKG2C) & Ser34-Ile179(CD94)

    Attributs du produit

    Recombinant Human NKG2C&CD94 Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus.It contains Glu98-Leu231(NKG2C)&Ser34-Ile179(CD94).

    Stérilité

    0.22 μm filtered

    niveau d'endotoxine

    Less than 1EU per μg by the LAL method.

    Biological Activity Comment

    The affinity constant of 1.65 μM as determined in SPR assay (Biacore T200). See testing image for detail.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    Buffer

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Date de péremption

    12 months
  • Antigène

    NKG2C & CD94

    Autre désignation

    NKG2C&CD94

    Sujet

    NKG2C&CD94 is a C-type lectin heterodimer on NK cells and CD8+ cytotoxic T-cells, it can recognize peptides derived from the intracellular proteins in the context of HLA-E. NKG2C&CD94 itself has no signal transduction function but is an activating receptor on the surface of NK cells that involved in driving the NK-cell expansion.

    Poids moléculaire

    15.3kDa (NKG2C)&17.9kDa (CD94). Due to glycosylation, the protein migrates to 30-50 kDa based on Tris-Bis PAGE result.
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