NKG2C & CD94 (AA 98-231) protein (His-Avi Tag)
Aperçu rapide pour NKG2C & CD94 (AA 98-231) protein (His-Avi Tag) (ABIN7275330)
Antigène
Type de proteíne
Origine
Source
Pureté
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Attributs du protein
- AA 98-231
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Purification/Conjugué
- His-Avi Tag
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Fonction
- Human NKG2C&CD94 Protein
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Séquence
- Glu98-Leu231(NKG2C) & Ser34-Ile179(CD94)
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Attributs du produit
- Recombinant Human NKG2C&CD94 Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus.It contains Glu98-Leu231(NKG2C)&Ser34-Ile179(CD94).
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Stérilité
- 0.22 μm filtered
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niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
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Biological Activity Comment
- The affinity constant of 1.65 μM as determined in SPR assay (Biacore T200). See testing image for detail.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Date de péremption
- 12 months
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- NKG2C & CD94
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Autre désignation
- NKG2C&CD94
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Sujet
- NKG2C&CD94 is a C-type lectin heterodimer on NK cells and CD8+ cytotoxic T-cells, it can recognize peptides derived from the intracellular proteins in the context of HLA-E. NKG2C&CD94 itself has no signal transduction function but is an activating receptor on the surface of NK cells that involved in driving the NK-cell expansion.
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Poids moléculaire
- 15.3kDa (NKG2C)&17.9kDa (CD94). Due to glycosylation, the protein migrates to 30-50 kDa based on Tris-Bis PAGE result.
Antigène
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