IgG1 Protein (C103S, D239E, L241E)
Aperçu rapide pour IgG1 Protein (C103S, D239E, L241E) (ABIN7316859)
Antigène
Voir toutes IgG1 ProtéinesType de proteíne
Origine
Source
Pureté
Classe de qualité
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Attributs du protein
- C103S, D239E, L241E
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Fonction
- Human IgG1 Fc (C103S, D239E, L241E) Protein, Tag Free (MALS verified)
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Séquence
- Pro 100 - Lys 330
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Attributs du produit
- Human IgG1 Fc (C103S, D239E, L241E), Tag Free is expressed from human 293 cells (HEK293). It contains AA Pro 100 - Lys 330 (Accession # P01857 (C103S, D239E, L241E).
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niveau d'endotoxine
- 1.0 EU per μg
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IgG1 (Fab Region) protein
Origine: Humain Hôte: Human Native >95 %
IgG1 (Fc Region) proteinOrigine: Humain Hôte: Human Native >95 %
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Commentaires
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This protein carries no "tag". The protein has a calculated MW of 26 kDa. The protein migrates as 31-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Stock
- -20 °C
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Stockage commentaire
- -20°C
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- IgG1
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Classe de substances
- Antibody
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Sujet
- Synonyms:IgG1,Description:Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
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Poids moléculaire
- 26 kDa
Antigène
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