IL-24 Protein (His tag)
Aperçu rapide pour IL-24 Protein (His tag) (ABIN7448047)
Antigène
Voir toutes IL-24 (IL24) ProtéinesType de proteíne
Origine
Source
Pureté
Classe de qualité
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Purification/Conjugué
- Cette IL-24 protéine est marqué à la His tag.
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Fonction
- Human IL-24 Protein, His Tag (BLI verified)
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Séquence
- Gln 52 - Leu 206
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Attributs du produit
- Human IL-24 Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Gln 52 - Leu 206 (Accession # Q13007-1).
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niveau d'endotoxine
- 1.0 EU per μg
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Interleukin 24 (IL24) (AA 51-206) (Active) protein (His tag)
IL24 Origine: Humain Hôte: Escherichia coli (E. coli) > 90 % CC, AcA Active
Interleukin 24 (IL24) (AA 58-167) protein (GST tag)IL24 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 24 (IL24) (AA 1-206) protein (GST tag)IL24 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 24 (IL24) (AA 1-207) protein (GST tag)IL24 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
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Commentaires
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This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 20.0 kDa. The protein migrates as 30-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Stock
- -20 °C
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Stockage commentaire
- -20°C
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- IL-24 (IL24) (Interleukin 24 (IL24))
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Autre désignation
- IL-24
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Sujet
- Synonyms:Interleukin-24,IL-24,Melanoma differentiation-associated gene 7 protein,MDA-7,Suppression of tumorigenicity 16 protein,IL24,MDA7,ST16,Description:Interleukin-24 (IL-24, also known as melanoma differentiation-associated gene-7) belongs to the family of IL-10-related cytokines, which includes IL-10, -19, -20, -22, -24 and -26. Interleukin 24 signals through two heterodimeric receptors: IL-20R1/IL-20R2 and IL-22R1/IL-20R2. Upon binding to its receptors, IL-24 induces rapid activation of Stat-1 and Stat-3 transcription factors, which appear to play a role in cell survival and proliferation . Structurally and functionally, IL-24 is highly conserved across species.IL-24 has been shown to possess cancer-specific apoptosis-inducing activity, and has therefore been suggested as a potential anti-cancer agent.
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Poids moléculaire
- 20.0 kDa
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy
Antigène
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