Tspan-8 Protein (His tag)
Aperçu rapide pour Tspan-8 Protein (His tag) (ABIN7317005)
Antigène
Voir toutes Tspan-8 (TSPAN8) ProtéinesType de proteíne
Origine
Source
Pureté
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Purification/Conjugué
- Cette Tspan-8 protéine est marqué à la His tag.
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Fonction
- Cynomolgus TSPAN8 Protein, His Tag
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Séquence
- Lys 110 - Ser 205
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Attributs du produit
- Cynomolgus TSPAN8, His Tag is expressed from human 293 cells (HEK293). It contains AA Lys 110 - Ser 205 (Accession # G7PI18-1).
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niveau d'endotoxine
- 1.0 EU per μg
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Tetraspanin 8 (TSPAN8) (AA 1-237) protein (His tag)
custom-made TSPAN8 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tetraspanin 8 (TSPAN8) (AA 1-235) protein (His tag)custom-made TSPAN8 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tetraspanin 8 (TSPAN8) (AA 110-205) protein (Fc Tag)TSPAN8 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tetraspanin 8 (TSPAN8) proteinTSPAN8 Origine: Humain Hôte: HEK-293 Cells Synthetic Nanodisc
Tetraspanin 8 (TSPAN8) (AA 110-205) protein (GST tag)TSPAN8 Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AA, AP
Tetraspanin 8 (TSPAN8) (AA 1-237) protein (GST tag)TSPAN8 Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AA, AP
Tetraspanin 8 (TSPAN8) protein (Fc Tag)TSPAN8 Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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Commentaires
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This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 12.7 kDa. The protein migrates as 17-20 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Stock
- -20 °C
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Stockage commentaire
- -20°C
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- Tspan-8 (TSPAN8) (Tetraspanin 8 (TSPAN8))
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Autre désignation
- TSPAN8
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Sujet
- Synonyms:CO-029,tetraspanin 8,TM4SF3,TM4SF3tspan-8,Transmembrane 4 superfamily member 3tetraspanin-8,TSPAN8,Tspan-8,Tumor-associated antigen CO-029,Description:Tspan8 is 1 of the 33 mammalian members of the tetraspanin family, composed of transmembrane proteins that organize laterally, together or with other membrane partners such as integrins, to form 'tetraspanin webs'. These platforms signal within cells to regulate many cellular processes: adhesion, migration, invasion or survival Tspan8 has been implicated in many types of cancer.Overexpression was reported in glioma and colorectal, esophageal, hepatic, gastric and pancreatic carcinoma. Tspan8 exerts a pro-invasive function by controlling cell-cell and cell-matrix interactions through its association with membrane partners such as α6β4 integrin-protein kinase C (PKC)-activated, E-cadherin, EpCAM, claudin-7 and CD44. Moreover, Tspan8 may be a promising new therapeutic target, as Tspan8-specific antibodies were shown to reduce cell motility, block tumor angiogenesis in vivo.
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Poids moléculaire
- 12.7 kDa
Antigène
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