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HLA-A*11:01 (AA 25-305), (Monomer) protein (Biotin,His-Avi Tag,KRAS)

Cette protéine Recombinant est exprimée dans HEK-293 Cells.
N° du produit ABIN7454303

Aperçu rapide pour HLA-A*11:01 (AA 25-305), (Monomer) protein (Biotin,His-Avi Tag,KRAS) (ABIN7454303)

Antigène

HLA-A*11:01

Type de proteíne

Recombinant

Origine

Humain

Source

  • 31
  • 7
  • 1
HEK-293 Cells

Pureté

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • Attributs du protein

    AA 25-305, Monomer

    Purification/Conjugué

    Biotin,His-Avi Tag,KRAS

    Fonction

    Biotinylated Human HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein

    Séquence

    Gly25-Thr305(HLA-A*11:01),Ile21-Met119(B2M)and VVVGAGGVGK peptide

    Specificité

    Uni-Prot: AAV53343.1 (HLA-A*11:01), P61769 (B2M), VVVGAGGVGK

    Attributs du produit

    Recombinant Biotinylated Human HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*11:01),Ile21-Met119(B2M) and VVVGAGGVGK peptide.

    Stérilité

    0.22 μm filtered

    niveau d'endotoxine

    Less than 1EU per μg by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    Buffer

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Date de péremption

    12 months
  • Antigène

    HLA-A*11:01

    Sujet

    Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.

    Poids moléculaire

    50.30 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Tris-Bis PAGE result.
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