RSPO1 Protein (AA 21-146) (Fc Tag)

N° du produit ABIN7491085

Cette protéine Recombinant RSPO1 est produite dans HEK-293 Cells.

Aperçu rapide pour RSPO1 Protein (AA 21-146) (Fc Tag) (ABIN7491085)

Antigène: RSPO1 (R-Spondin 1 (RSPO1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Détail du produit

Attributs du protein: AA 21-146

Purification/Conjugué: Cette RSPO1 protéine est marqué à la Fc Tag.

Fonction: Recombinant human RSPO1(21-146) protein with C-terminal human Fc tag

Specificité: RSPO1 (21-146) (Ser21-Ala146) hFc (Glu99-Ala330)

Attributs du produit: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: RSPO1 (R-Spondin 1 (RSPO1))

Autre désignation: RSPO1

Sujet: This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

Poids moléculaire: predicted molecular mass of 39.9 kDa after removal of the signal peptide. The apparent molecular mass of RSPO1(21-146)-hFc is 35-55 kDa due to glycosylation.

UniProt: Q2MKA7