IL-37 Protéine

N° du produit ABIN7455618

Protéine Recombinant IL-37 exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour IL-37 Protéine (ABIN7455618)

Antigène: IL-37 (IL37) (Interleukin 37 (IL37))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)

Pureté: Greater than 95 % as determined by reducing SDS-PAGE.

Détail du produit

Fonction: Recombinant Human Interleukin-37 is produced by our E.coli expression system and the target gene encoding Lys53-Asp218 is expressed.

Attributs du produit: Extracellular Domain Protein

Purification: Affinity purification

Information d'application

Indications d'application: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 2 mM DTT, pH 7.4.

Agent conservateur: Dithiothreitol (DTT)

Précaution d'utilisation: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: IL-37 (IL37) (Interleukin 37 (IL37))

Autre désignation: IL-37

Sujet: Interleukin-37,FIL1 Zeta,IL-1X,Interleukin-1 Family Member 7,IL-1F7,Interleukin-1 Homolog 4,IL-1H,IL-1H4,Interleukin-1 Zeta,IL-1 Zeta,Interleukin-1-Related Protein,IL-1RP1,Interleukin-23,IL-37,IL37,FIL1Z,IL1F7,IL1H4,IL1RP1
Human Interleukin family 1 Member 7 (IL1F7) is a member of the Interleukin 1 cytokine family. Five alternatively spliced transcript variants encoding distinct isoforms have been reported with distinct expression profiles. The longest IL1F7 transcript, referred to as IL1F7b or IL1F7 isoform 1, encodes a 218 amino acid residues proprotein containing a 45 amino acid propeptide, which is cleaved to generate mature protein. IL1F7b binds to IL18 Ra with low affinity but does not exert any IL18 agonistic or antagonistic effects. IL1F7b also binds interleukin 18 binding protein (IL-18BP), an inhibitory binding protein of interleukin 18 (IL-18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL-18.

Poids moléculaire: 18.7 KDa

UniProt: Q9NZH6