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PDGF-BB Homodimer Protéine

Cette protéine Recombinant est exprimée dans Escherichia coli (E. coli).
N° du produit ABIN7455626

Aperçu rapide pour PDGF-BB Homodimer Protéine (ABIN7455626)

Antigène

PDGF-BB Homodimer

Type de proteíne

Recombinant

Origine

  • 8
  • 7
  • 3
Humain

Source

  • 12
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Pureté

Greater than 98 % as determined by reducing SDS-PAGE.
  • Fonction

    Recombinant Human Platelet-Derived Growth Factor BB is produced by our E.coli expression system and the target gene encoding Ser82-Thr190 is expressed.

    Attributs du produit

    Extracellular Domain Protein

    Purification

    Affinity purification
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM NaAc-HAc, pH 4.5.

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Date de péremption

    12 months
  • Antigène

    PDGF-BB Homodimer

    Autre désignation

    PDGF-BB

    Sujet

    Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.

    Poids moléculaire

    12.42 KDa

    UniProt

    P01127
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