Recombinant Human Platelet-Derived Growth Factor BB is produced by our E.coli expression system and the target gene encoding Ser82-Thr190 is expressed.
Attributs du produit
Extracellular Domain Protein
Pureté
Greater than 98 % as determined by reducing SDS-PAGE.
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 97 % by SDS-PAGE.
Active
Restrictions
For Research Use only
Format
Lyophilized
Buffer
a 0.2 μm filtered solution of 20 mM NaAc-HAc, pH 4.5.
Stock
-20 °C
Stockage commentaire
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
PDGFBB, PDGF-BB Description: Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.