Vitronectin Protein (VTN) (His tag)

N° du produit ABIN7455636

Protéine Recombinant Vitronectin exprimée dans HEK-293 Cells.

Aperçu rapide pour Vitronectin Protein (VTN) (His tag) (ABIN7455636)

Antigène: Vitronectin (VTN)

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Application: Immunoassay (IA), Affinity Measurement (AM), Antibody Drug Assay (ADA), Screening Assay (ScA)

Pureté: Greater than 90 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette Vitronectin protéine est marqué à la His tag.

Fonction: Recombinant Human Vitronectin is produced by our Mammalian expression system and the target gene encoding Val62-Leu478 is expressed with a 6His tag at the C-terminus.

Attributs du produit: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Information d'application

Indications d'application: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Commentaires:

The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: Vitronectin (VTN)

Autre désignation: Vitronectin

Sujet: Complement S-protein,epibolin,Serum Spreading Factor,Serum-spreading factor,Somatomedin B,S-protein,V75,Vitronectin,VN,VNT,VTN
Vitronectin, also known as VTN, is a large glycoprotein found in blood and the extracellular matrix (ECM). Vitronectin is a plasma glycoprotein implicated as a regulator of diverse physiological process, including blood coagulation, fibrinolysis, pericellular proteolysis, complement dependent immune responses, and cell attachment and spreading. Blocking of Hic(a member of the pneumococcal surface protein C (PspC) family) by specific antiserum or genetic deletion significantly reduced pneumococcal binding to soluble and immobilised vitronectin and to Factor H, respectively. In addition, Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.

Poids moléculaire: 48.3 KDa

Pathways: Autophagy, Smooth Muscle Cell Migration