CCL16 Protéine

N° du produit ABIN7455689

Détail du produit

Antigène: CCL16 (Chemokine (C-C Motif) Ligand 16 (CCL16))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Fonction: Recombinant Human C-C Motif Chemokine 16 is produced by our E.coli expression system and the target gene encoding Gln24-Gln120 is expressed.

Attributs du produit: Extracellular Domain Protein

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Stock: -20 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: CCL16 (Chemokine (C-C Motif) Ligand 16 (CCL16))

Autre désignation: CCL16 (CCL16 Produits)

Synonymes: CKb12 Protein, HCC-4 Protein, ILINCK Protein, LCC-1 Protein, LEC Protein, LMC Protein, Mtn-1 Protein, NCC-4 Protein, NCC4 Protein, SCYA16 Protein, SCYL4 Protein, C-C motif chemokine ligand 16 Protein, CCL16 Protein, Ccl16 Protein

Sujet: C-C Motif Chemokine 16, Chemokine CC-4, HCC-4, Chemokine LEC, IL-10-Inducible Chemokine, LCC-1, Liver-Expressed Chemokine, Lymphocyte and Monocyte Chemoattractant, LMC, Monotactin-1, MTN-1, NCC-4, Small-Inducible Cytokine A16, CCL16, ILINCK, NCC4, SCYA16CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. CCL16 is distantly related to other CC chemokines, showing less than 30 % sequence identity. CCL16 elicits its effects on cells by interacting with cell surface chemokine receptors such as CCR1, CCR2, CCR5 and CCR8. Recombinant CCL16 has been shown to chemoattract human monocytes and THP1 cells but not resting lymphocytes nor neutrophils. CCL16 has potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. CCL16ninduces a calcium flux in THP1 cells that can be desensitized by prior exposure to RANTES, suggesting that CCL16 and RANTES share the same receptor in THP1 cells.

Poids moléculaire: 11 KDa

UniProt: O15467