Azurocidin Protein (AA 27-248) (His tag)
Aperçu rapide pour Azurocidin Protein (AA 27-248) (His tag) (ABIN7491379)
Antigène
Voir toutes Azurocidin (AZU1) ProtéinesType de proteíne
Origine
Source
Pureté
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Attributs du protein
- AA 27-248
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Purification/Conjugué
- Cette Azurocidin protéine est marqué à la His tag.
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Fonction
- Recombinant Human AZU1 Protein with C-terminal 6xHis tag
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Specificité
- AZU1 (Ile27-Pro248) 6xHis tag
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Attributs du produit
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Date de péremption
- 12 months
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- Azurocidin (AZU1) (Azurocidin 1 (AZU1))
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Autre désignation
- AZU1
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Sujet
- Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq, Nov 2015]
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Poids moléculaire
- predicted molecular mass of 24.9 kDa after removal of the signal peptide. The apparent molecular mass of AZU1-His is 35-55 kDa due to glycosylation.
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UniProt
- P20160
Antigène
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