CXCR3 Protein-VLP
Aperçu rapide pour CXCR3 Protein-VLP (ABIN7488804)
Antigène
Voir toutes CXCR3 ProtéinesType de proteíne
Origine
Source
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Fonction
- Human CXCR3 Full Length Protein (VLP)
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Séquence
- Val 2 - Leu 368
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Attributs du produit
- Human CXCR3 Full Length Protein-VLP is expressed from human 293 cells (HEK293). It contains AA Val 2 - Leu 368 (Accession # P49682-1).
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niveau d'endotoxine
- 1.0 EU per μg
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!Découvrez nos protéines personnalisées prédéfinies et nos services de protéines sur mesure !ProduitSystème d'expressionConjuguéOriginPrix à partir deSystème d'expression HEK-293 CellsConjugué His tagOrigin HumanPrix à partir de 16.256,82 €Système d'expression Cell-free protein synthesis (CFPS)Conjugué Strep TagOrigin HumanPrix à partir de 18.117,43 €Votre projet nécessite-t-il une personnalisation supplémentaire ? Contactez-nous et découvrez nos solutions protéiques sur mesure
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Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 1-53) protein (mFc Tag)
CXCR3 Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 1-367) protein (His tag)custom-made CXCR3 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 1-368) protein (His tag)custom-made CXCR3 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 1-53) protein (Fc Tag)CXCR3 Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-X-C Motif) Receptor 3 (CXCR3) proteinCXCR3 Origine: Humain Hôte: HEK-293 Cells Synthetic Nanodisc
Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 1-368) protein (GST tag)CXCR3 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 1-53) protein (GST tag)CXCR3 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 121-220) protein (GST tag)CXCR3 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, Arginine, pH 7.4
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Stock
- -80 °C
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Stockage commentaire
- -70°C
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- CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))
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Autre désignation
- CXCR3
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Sujet
- Chemokines are proteins which induce chemotaxis, promote differentiation of immune cells, and cause tissue extravasation. Given these properties, their role in anti-tumor immune response in the cancer environment is of great interest. Although immunotherapy has shown clinical benefit for some cancer patients, other patients do not respond. One of the mechanisms of resistance to checkpoint inhibitors may be chemokine signaling. The CXCL9, -10, -11/CXCR3 axis regulates immune cell migration, differentiation, and activation, leading to tumor suppression (paracrine axis). However, there are some reports that show involvements of this axis in tumor growth and metastasis (autocrine axis). Thus, a better understanding of CXCL9, -10, -11/CXCR3 axis is necessary to develop effective cancer control.
Antigène
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