tau-441 (P301L) protein (His tag)

N° du produit ABIN7482544

Protéine Recombinant exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour tau-441 (P301L) protein (His tag) (ABIN7482544)

Antigène: tau-441

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: 90 %

Détail du produit

Attributs du protein: P301L

Purification/Conjugué: His tag

Fonction: Human Tau-441 / 2N4R (P301L) Protein, His Tag

Séquence: Met 1 - Leu 441

Attributs du produit: Human Tau-441 (P301L), His Tag is expressed from E.coli cells. It contains AA Met 1 - Leu 441 (Accession # P10636-8 (P301L).

niveau d'endotoxine: 1.0 EU per μg

Information d'application

Commentaires:

This protein carries a polyhistidine tag at the N-terminus. (10xHis) The protein has a calculated MW of 47.8 kDa. The protein migrates as 38-66 kDa under reducing (R) condition (SDS-PAGE).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: tau-441

Sujet: Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

Poids moléculaire: 47.8 kDa